Supplementation with vitamins A, C, and E is “strongly associated” with lower levels of colon cancer, according to a new study.
The research, published in the journal Cancer Causes Control, claims that supplementation with multivitamins, especially those containing vitamins A, C, E, and folate are linked to lower risks of colon cancer.
Vitamins A, C, E, and folic acid have been suggested to reduce the risks of colon cancer because of their high anti-oxidant power and potential anti-cancer properties.
The aims of the new research were to evaluate the associations between vitamins A, C, and E and risk of colon cancer, using primary data from 13 previous cohort studies with over 650,000 participants.
Dietary intakes of vitamin A, C, and E were found to be not associated with colon cancer risk. However the researchers reported a strong inverse association for the vitamins when looking at dietary and supplementary multivitamin intake.
SAS.overlays[ ‘TextAd’ ] = clicktag; Multivitamin use – especially in combination with individual vitamin supplements – was reported to be significantly associated with a reduced colon cancer risk, whilst raised folate intake was also related to a lower risk.
The authors noted that there are “plausible biologic mechanisms support our results”, suggesting total vitamin C and E intakes may be associated with a decreased risk of colon cancer due to their ability to break “free radical chain reactions”, and act as electron donors to reduce reactive radicals and iron.